Pentachlorophenol decreases ATP levels in human natural killer cells
نویسندگان
چکیده
منابع مشابه
Human natural killer cells.
Natural killer (NK) cells were discovered more than 30 years ago. NK cells are large granular lymphocytes that belong to the innate immune system because unlike T or B lymphocytes of the adaptive or antigen-specific immune system, NK cells do not rearrange T-cell receptor or immunoglobulin genes from their germline configuration. During the past 2 decades there has been a substantial gain in ou...
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Background: Schizophrenia has been associated with altered immunity. Different studies regarding natural killer cell activity (NKA) in schizophrenic patients have shown inconsistent results. Objectives: To evaluate NK cell activity in schizophrenic patients in comparison with healthy control individuals. Methods: 30 medication-free schizophrenic patients and 41 healthy sex, age and smoking st...
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Background: Invariant natural killer cells (iNKT) are an important immunoregulatory T cell subset. Currently several flow cytometry-based approaches exist for the identifi-cation of iNKT cells, which rely on using the 6B11 monoclonal antibody or a combina-tion of anti-Vα24 and anti-Vβ11 antibodies. Objective: The aim of this study was to compare the ability of two flow cytometry-based methods f...
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Natural killer (NK) cells are innate lymphocytes that play a critical role in early host defense against viruses. Through their cytolytic capacity and generation of cytokines and chemokines, NK cells modulate the activity of other components of the innate and adaptive immune systems and have been implicated in the initiation or maintenance of autoimmune responses. This review focuses on recent ...
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Granulocytes and monocytes are known to phagocytose and kill numerous varieties of bacteria and parasites. This function is intimately associated with an early event called the "respiratory burst," which includes the generation of 02and H202 (1). These and other highly reactive molecular species can easily be detected in the presence of luminol or other readily oxidized substrates by the emissi...
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ژورنال
عنوان ژورنال: Journal of Applied Toxicology
سال: 2008
ISSN: 0260-437X,1099-1263
DOI: 10.1002/jat.1367